Maybe it's just me but I see quite a difference between the two approaches
Yes, for many reasons there really is a big difference. The strong emphasis in Epicureanism on choices and avoidances, and personal responsibility leads to a much better outcome, I think.
If a person ends up repeatedly chanting that desire, aversion, and ignorance are inexhaustable (by nature), then they are in a sense giving away their power and also stating a distrust in the ability of the mind to reason correctly.