It's been a while and I don't recall the details of the Santayana essay. What's interesting to me in this discussion is the connection between excellent scholarship in some aspects of the essay combined with the total dismissal of Epicurus in other parts. It seems as though one devoted to excelling in scholarship just can't comprehend or stomach the ultimate simplicity and obviousness of Epicurus' insights.
Of course part of Epicurus' project was to show the futility of over-reliance on the intellect. So the intellectual probably feels compelled to demean and discredit Epicurus. The tragedy, to me, is how over the millennia those who make a fancy argument can blind so many to basic truths.