Does this seem like a ping pong game? It's a terrible idea to try to "translate" the ten commandments but at the same time it's a great exercise!
I do think both perspectives are true and this highlights how central "context" is to the Epicurean worldview. You've picked a particular context and within that context we can work toward something that's helpful, but at the same time we have to realize that out of its context it could actually be harmful.
I really do think this is why the PDs read as they do. They are sort of "principles" that don't necessarily lead TO a particular direction for a particular life, but they lead AWAY from major pitfalls that are pitfalls for everyone.
I didn't finish listening to the Hitchens talk but I think from past observation that he is subject to a major danger that people have to take an approach that is something like "I too believe that there are absolute rules for being a good person - but those guys got the rules wrong and I can give you the correct list."
The Epicurus approach is more like "You've got to understand that there is NO single list of rules that apply to everyone at all times and all places to tell them affirmatively what to do in every circumstance. But I can tell you how the universe works (the physics) and how to use your head (the canonics) and then I can also tell you the major pitfalls that everyone confronts and how to avoid them. Then after that you're as equipped as anyone can be to use your life in your context to pursue the general goal that everything else points to."