I'd like to add an observation in relation to the great stink, mentioned by Joshua in this episode regarding disease and plagues.
The importance of Edwin Chadwick and his role to resolve cholera in London at that time is missing in the equation (unless I missed it myself when listening, sorry Joshua if that's the case).
He was the main character to develop drainage and sewerage. The river Thames was not the only problem, my understanding is that people used to walk on excrement, so cholera killed thousands of Londoners.
Therefore, it was an urban solution applied to public health. I admire EC, and I thought he should be considered in this particular debate as well, that's all.