Here is an article why the reliance on models/theories in science and the realism-anti-realism dispute in the philosophy of science should not turn us into Sceptics:
"When is a Fact a Fact?": A Conversation with Peter Vickers
I found the link at Philosophy Matters on: Facebook
I understand 5 sigma certainty is the gold standard: ![]()
Why do physicists mention “five sigma” in their results? | CERN