Verse 134 catches my eye:
Because of this, it is better to follow the stories of the gods than to be enslaved by the deterministic decrees of the old natural philosophers, because necessity is not moved by prayer;
φυσικῶν "of the inquirers into nature, natural philosophers esp. of the Ionic and other pre-Socratic philosophers"
τῇτῶνφυσικῶν εἱμαρμένῃ "the decrees of the old natural philosophers" i.e., determinists, those decreeing fate is all-powerful
Is there anything more to it than Epicurus simply criticising believe in fate and therefore criticising giving up on deciding one's own destiny? (Consequently, emphasising the importance of artisting one's own life)
Is there any given evidence that these philosophers drove their own agendas by declaring what the fates are? If yes, is there anything comparable to it nowadays?
One could also think of it as a critique of the argument: "This is science!" (and therefore truth - trust me, not your senses). Do you think this is appropriate or does it overstretch the argument?